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June 06, 2005
Depression Gene May Weaken Mood-Regulating Circuit
The gene codes for the serotonin transporter, the protein in brain cells that recycles the chemical messenger after it's been secreted into the synapse, the gulf between cells. Since the most widely prescribed class of antidepressants act by blocking this protein, researchers have focused on possible functional consequences of a slight variation in its DNA sequence across individuals. Everyone inherits two copies of the gene, one from each parent, which comes in two common versions: short and long. The short version makes less protein, resulting...
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Posted on June 6, 2005 07:33 PM by antide275.
Filed in Mental Health Update under antidepressants.
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